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UGT2B17 antibody, Internal

Anti-UGT2B17 antibody, Internal used in Western Blot (WB). GTX81884
Anti-UGT2B17 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX81884

Cat. No. GTX81884

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IHC

Reactivity

 Human
Package
400 μl ($399)
See all UGT2B17 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:10-1:50
IHC Assay dependent
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 119-147 amino acids from the Central region of human UGT2B17.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

RRID

AB_11161900

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

UDP glucuronosyltransferase family 2 member B17 , BMND12 , UDPGT2B17

Cellular Localization

Endoplasmic reticulum membrane

Background

This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.[provided by RefSeq, Apr 2010]

Database

Research Area

DATA IMAGES

Anti-UGT2B17 antibody, Internal used in Western Blot (WB). GTX81884

GTX81884 WB Image

WB analysis of Y79 cell lysate (35ug/lane) using GTX81884 UGT2B17 antibody, Internal.

Anti-UGT2B17 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX81884

GTX81884 IHC-P Image

IHC-P analysis of human prostate carcinoma using GTX81884 UGT2B17 antibody, Internal.

REFERENCE

Application Reference

Zimmer BM et al. Oncotarget 2021; 12 (19) : 1886-1902 Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer.
Reactivity : Human
Wang S et al. Carcinogenesis 2019; (Epub) Trans-acting nonsynonymous variant of FOXA1 predisposes to hepatocellular carcinoma through modulating FOXA1-ER帢 transcriptional program and may have undergone natural selection.
Xiang C et al. FASEB J 2015; 29 (5) : 1986-98 Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer.
Application : IHC
Reactivity : Human
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399