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ULBP2 antibody [7F33]

Cat. No. GTX53048

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7F33

Isotype

 IgG2

Application

 FACS, Neutralizing/Inhibition

Reactivity

 Human
Package
100 μg ($399)
See all ULBP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 1:50 - 1:100
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant ULBP-2

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ALCANalpha , N2DL2 , NKG2DL2 , RAET1H , UL16 binding protein 2 , ULBP2

Cellular Localization

Cell membrane,Endoplasmic reticulum,Secreted

Background

This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015]

Database

Research Area

REFERENCE

Application Reference

Jia Z Shen et al. Cell 2020; S0092-8674 (20) : 31614-7 FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells.
Application : FACS
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399