GeneTex
United States (US)

UPK1B antibody

GTX32032_3164_WB_20180221_18121410_967.jpg
GTX32032_1722_IHC-P_20180221_18121410_962.jpg
GTX32032_1723_IHC-P_20180221_18121410_402.jpg

Cat No. GTX32032

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 - 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

30 kDa. ( Note )

Positive Control

Human Kidney Tissue Lysate(GTX29995)

Specificity/Sensitivity

At least two isoforms of UPK1B are known to exist; this antibody will recognize both isoforms. UPK1B antibody is predicted to not cross-react with other tetraspanin protein family members.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

UPK1B antibody was raised against a 17 amino acid synthetic peptide near the center of human UPK1B.The immunogen is located within amino acids 110 - 160 of UPK1B.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Uroplakin 1B,Tspan20,Upib,Upk1,Upk1B

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX32032_3164_WB_20180221_18121410_967.jpg

GTX32032 WB Image

WB analysis of human kidney tissue lysate in the (A) absence and (B) presence of blocking peptide using GTX32032 UPK1B antibody.
Working concentration : 1 μg/ml

GTX32032_1722_IHC-P_20180221_18121410_962.jpg

GTX32032 IHC-P Image

IHC-P analysis of human bladder tissue using GTX32032 UPK1B antibody.
Working concentration : 5 μg/ml

GTX32032_1723_IHC-P_20180221_18121410_402.jpg

GTX32032 IHC-P Image

IHC-P analysis of human bladder tissue using GTX32032 UPK1B antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 339