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UQCRB antibody

Anti-UQCRB antibody used in Western Blot (WB). GTX130895
Anti-UQCRB antibody used in IHC (Paraffin sections) (IHC-P). GTX130895
Anti-UQCRB antibody used in IHC (Paraffin sections) (IHC-P). GTX130895

Cat. No. GTX130895

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all UQCRB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000-1:10000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

14 kDa. ( Note )

Positive Control

mouse liver , human liver

Predict Reactivity

Bovine, Chicken, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.13 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human UQCRB. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2886379

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ubiquinol-cytochrome c reductase binding protein , MC3DN3 , QCR7 , QP-C , QPC , UQBC , UQBP , UQCR6 , UQPC

Cellular Localization

Mitochondrion inner membrane

Background

This gene encodes a protein which is part of the ubiquinol-cytochrome c oxidoreductase complex which contains ten nuclear-encoded and one mitochondrial-encoded subunits. The encoded protein binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. Mutations in this gene are associated with mitochondrial complex III deficiency. A pseudogene has been described on the X chromosome. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-UQCRB antibody used in Western Blot (WB). GTX130895

GTX130895 WB Image

UQCRB antibody detects UQCRB protein by western blot analysis. Human tissue extracts (30 μg) and mouse tissue extracts (50 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with UQCRB antibody (GTX130895) diluted at 1:5000.

Anti-UQCRB antibody used in IHC (Paraffin sections) (IHC-P). GTX130895

GTX130895 IHC-P Image

UQCRB antibody detects UQCRB protein at mitochondria in rat intestine by immunohistochemical analysis.
Sample: Paraffin-embedded rat intestine.
UQCRB antibody (GTX130895) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-UQCRB antibody used in IHC (Paraffin sections) (IHC-P). GTX130895

GTX130895 IHC-P Image

UQCRB antibody detects UQCRB protein at mitochondria in mouse liver by immunohistochemical analysis.
Sample: Paraffin-embedded mouse liver.
UQCRB antibody (GTX130895) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

Application Reference

Giusti L et al. Neuroscience 2019; (Epub) Brain mitochondrial proteome alteration driven by creatine deficiency suggests novel therapeutic venues for creatine deficiency syndromes.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399
$ 169