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USH1C antibody

Anti-USH1C antibody used in Western Blot (WB). GTX19045
Anti-USH1C antibody used in IHC (Paraffin sections) (IHC-P). GTX19045

Cat No. GTX19045

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
50 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.1-0.3μg/ml
IHC-P 10μg/ml

Note :

IHC-P
Human Kidney, shows diffuse cytopasmic staining in epithelial cells of renal tubules.

Not tested in other applications.

Calculated MW

62 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX19045-PEP).

Product Note

This antibody is expected to recognize both reported isoforms (NP_005700.2 and NP_710142.1).

Predict Reactivity

Mouse, Rat, Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence DRKVAREFRHKVD-C, from the N Terminus of the protein sequence according to NP_005700.2; NP_710142.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

USH1 protein network component harmonin , AIE-75 , DFNB18 , DFNB18A , NY-CO-37 , NY-CO-38 , PDZ-45 , PDZ-73 , PDZ-73/NY-CO-38 , PDZ73 , PDZD7C , ush1cpst

Cellular Localization

Cytoplasm, cytosol , Cytoplasm, cytoskeleton

Background

This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Database

Research Area

DATA IMAGES

Anti-USH1C antibody used in Western Blot (WB). GTX19045

GTX19045 WB Image

WB analysis of HEK293 lysate using GTX19045 USH1C antibody.
Dilution : 0.1μg/ml
Loading : 35μg protein in RIPA buffer

Anti-USH1C antibody used in IHC (Paraffin sections) (IHC-P). GTX19045

GTX19045 IHC-P Image

IHC-P analysis of human kidney using GTX19045 USH1C antibody.
Antigen retrieval : citrate buffer pH 6
Dilution : 10μg/ml

REFERENCE

There are currently no references for USH1C antibody (GTX19045). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for USH1C antibody (GTX19045). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf