*Optimal dilutions/concentrations should be determined by the researcher.
Human Kidney, shows diffuse cytopasmic staining in epithelial cells of renal tubules.
Not tested in other applications.
The peptide used to generate this antibody is available for purchase (GTX19045-PEP).
This antibody is expected to recognize both reported isoforms (NP_005700.2 and NP_710142.1).
Mouse, Rat, Bovine(>80% identity)
Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Peptide with sequence DRKVAREFRHKVD-C, from the N Terminus of the protein sequence according to NP_005700.2; NP_710142.1.
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
USH1 protein network component harmonin , AIE-75 , DFNB18 , DFNB18A , NY-CO-37 , NY-CO-38 , PDZ-45 , PDZ-73 , PDZ-73/NY-CO-38 , PDZ73 , PDZD7C , ush1cpst
Cytoplasm, cytosol , Cytoplasm, cytoskeleton
This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
GTX19045 WB Image
WB analysis of HEK293 lysate using GTX19045 USH1C antibody.
Dilution : 0.1μg/ml
Loading : 35μg protein in RIPA buffer
GTX19045 IHC-P Image
IHC-P analysis of human kidney using GTX19045 USH1C antibody.
Antigen retrieval : citrate buffer pH 6
Dilution : 10μg/ml