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USP2 antibody [1738CT331.50.87]

Anti-USP2 antibody [1738CT331.50.87] used in Western Blot (WB). GTX03924

Cat. No. GTX03924

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1738CT331.50.87

Isotype

 IgG1

Application

 WB

Reactivity

 Human, Monkey
Package
100 μl ($399)
See all USP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:2000
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein between 1-258 amino acids from human USP2.

Purification

Protein G purified followed by dialysis against PBS

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ubiquitin specific peptidase 2 , UBP41 , USP9

Cellular Localization

Cytoplasm , Membrane

Background

This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-USP2 antibody [1738CT331.50.87] used in Western Blot (WB). GTX03924

GTX03924 WB Image

WB analysis of various lysates using GTX03924 USP2 antibody [1738CT331.50.87].
Lane 1 : MCF-7
Lane 2 : PC-3
Lane3 : COS-7
Lane 4 : Du145
Lane 5 : SK-BR-3
Dilution : 1:2000
Loading : 20 μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 399