GeneTex

  • Country / Location Selection

United States (US)

VCAM1 / CD106 antibody [M/K-2]

Cat. No. GTX19569

Host

 Rat

Clonality

 Monoclonal

Clone Name

 M/K-2

Isotype

 IgG1

Application

 ICC/IF, IHC-Fr

Reactivity

 Mouse
Package
100 μg ($399)
See all VCAM1 / CD106 products

APPLICATION

Application Note

IF: Use at an assay dependent dilution. IHC-Fr: (Not suitable for use with parafin sections) Use at an assay dependent dilution. FuncS: Use at an assay dependent dilution. Studies of cell-cell interaction. Cell adhesion assays. Inhibition of lymphopoiesis in Whitlock-Witte long term marrow cultures. Immunoprecipitation of the VCAM1 integrin complex. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

81 kDa. ( Note )

Product Note

Present on the +/+ 2.4 stromal cell clone, large cells in bone marrow, and a subset of thymic macrophages. The stromal cell antigen is also detectable on the EOMA and BMS2 endothelial cell lines. Reacts with all known isoforms of murine VCAM-1. Murine vascular adhesion molecule (VCAM1), single chain glycoprotein of Mr100-kDa (under reducing conditions).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

10mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

BALB/3T3 and +/+ 2.4 cells.

Purification

Protein G affinity purified.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

vascular cell adhesion molecule 1 , CD106 , INCAM-100

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

Database

Research Area

REFERENCE

There are currently no references for VCAM1 / CD106 antibody [M/K-2] (GTX19569). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for VCAM1 / CD106 antibody [M/K-2] (GTX19569). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399