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VCP antibody [Hs-14]

Anti-VCP antibody [Hs-14] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX23983

Cat. No. GTX23983

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 Hs-14

Isotype

 IgM

Application

 WB, ICC/IF, FACS

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all VCP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
FACS Assay dependent
Not tested in other applications.

Calculated MW

89 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

TBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization.

Purification

Purified by precipitation and chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ALS14 , CMT2Y , HEL220 , HELS70 , IBMPFD , IBMPFD1 , TERA , VCP , p97 , valosin containing protein , ATPase p97

Cellular Localization

Cytoplasm,Cytosol,Endoplasmic reticulum,Nucleus

Background

This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-VCP antibody [Hs-14] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX23983

GTX23983 ICC/IF Image

ICC/IF analysis of acetone-permeabilized human sperms (normal spermiogram) using GTX23983 VCP antibody [Hs-14].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399