APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 0.2-2.5 ug/ml |
| 2-10 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
human B lymphoblast , human fetal heart , human fetal muscle
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human VDAC3
Purification
Affinity Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
voltage dependent anion channel 3 , HD-VDAC3 , VDAC-3
Cellular Localization
Mitochondrion outer membrane
Background
This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Database
Research Area
DATA IMAGES
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GTX47681 WB Image
WB analysis of human fetal muscle tissue using GTX47681 VDAC3 antibody at 1μg/ml.
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GTX47681 WB Image
WB analysis of human B lymphoblast cells using GTX47681 VDAC3 antibody at 1μg/ml.
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GTX47681 IHC-P Image
IHC-P analysis of human lung tissue using GTX47681 VDAC3 antibody at 4.0-8.0μg/ml.
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GTX47681 WB Image
WB analysis of human fetal heart tissue using GTX47681 VDAC3 antibody at 1μg/ml.
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GTX47681 WB Image
WB analysis of human fetal heart tissue using GTX47681 VDAC3 antibody at 0.2-1μg/ml.
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REFERENCE
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REVIEW
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