GeneTex

  • Country / Location Selection

United States (US)

VE-Cadherin antibody [8A03]

Anti-VE-Cadherin antibody [8A03] used in Western Blot (WB). GTX52465
Anti-VE-Cadherin antibody [8A03] used in IHC (Paraffin sections) (IHC-P). GTX52465

Cat. No. GTX52465

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8A03

Isotype

 IgG1

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($399)
See all VE-Cadherin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000 - 1:2000
IHC-P Assay dependent
ELISA 1:1000 - 1:3000
Not tested in other applications.

Calculated MW

88 kDa. ( Note )

Product Note

In western blots this antibody shows no cross-reactivity with E-Cadherin, and P-Cadherin.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Extracellular domain of Human VECadherin recombinant protein

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD144 , CDH5 , cadherin 5 , VE Cadherin , VE-Cadherin , Cadherin 5 , 7B4

Cellular Localization

Cell junction,Cell membrane

Background

This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-VE-Cadherin antibody [8A03] used in Western Blot (WB). GTX52465

GTX52465 WB Image

WB analysis of HUVECs cell lysates using GTX52465 VE-Cadherin antibody [8A03].

Anti-VE-Cadherin antibody [8A03] used in IHC (Paraffin sections) (IHC-P). GTX52465

GTX52465 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52465 VE-Cadherin antibody [8A03].

REFERENCE

There are currently no references for VE-Cadherin antibody [8A03] (GTX52465). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for VE-Cadherin antibody [8A03] (GTX52465). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Package List Price ($)
$ 399