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VE-Cadherin antibody [8E5]

Anti-VE-Cadherin antibody [8E5] used in IHC (Paraffin sections) (IHC-P). GTX34239
Anti-VE-Cadherin antibody [8E5] used in IHC (Paraffin sections) (IHC-P). GTX34239

Cat No. GTX34239

Host Mouse
Clonality Monoclonal
Clone Name 8E5
Isotype IgG1
Application IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

88 kDa. ( Note )

Specificity/Sensitivity

VE-Cadherin Mouse Monoclonal Antibody (8E5) detects endogenous levels of CDH5
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic Peptide of VE-Cadherin

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cadherin 5,7B4,Cd144,Cdh5

Background

This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-VE-Cadherin antibody [8E5] used in IHC (Paraffin sections) (IHC-P). GTX34239

GTX34239 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Heart Tissue using VE-Cadherin Mouse Monoclonal Antibody diluted at 1:200.

Anti-VE-Cadherin antibody [8E5] used in IHC (Paraffin sections) (IHC-P). GTX34239

GTX34239 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Heart Tissue using VE-Cadherin Mouse Monoclonal Antibody diluted at 1:200.

Package List Price ($)
$ 319