*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
This antibody recognizes an epitope within amino acid residues 1-251 located in the extracellular domain of human VEGF (vascular endothelial growth factor) receptor 1 (VEGFR-1), otherwise known as Flt-1.
Tissue Culture Supernatant with 10mM Sodium Azide, 10% Foetal Bovine Serum
Extracellular domain of recombinant human VEGFR-1
Tissue Culture Supernatant
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
VEGFR1 Antibody , FLT Antibody , FLT-1 Antibody , fms-related tyrosine kinase 1 Antibody , FLT1 Antibody
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]