GeneTex
United States (US)

VEGF Receptor 1 antibody [Flt-19]

Cat No. GTX38812

Host Mouse
Clonality Monoclonal
Clone Name Flt-19
Isotype IgG1
Application IHC-Fr, IP, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-Fr Assay dependent
IP Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

151 kDa kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes an epitope within amino acid residues 1-251 located in the extracellular domain of human VEGF (vascular endothelial growth factor) receptor 1 (VEGFR-1), otherwise known as Flt-1.
PROPERTIES

Form

Liquid

Buffer

Tissue Culture Supernatant with 10mM Sodium Azide, 10% Foetal Bovine Serum

Antigen Species

Human

Immunogen

Extracellular domain of recombinant human VEGFR-1

Purification

Tissue Culture Supernatant

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

VEGFR1 Antibody , FLT Antibody , FLT-1 Antibody , fms-related tyrosine kinase 1 Antibody , FLT1 Antibody

Background

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
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Database

Research Area