GeneTex
United States (US)

VEGF Receptor 1 antibody

VEGF-receptor-1-antibody-GTX22350-IHC-1_18121411_530.jpg
VEGF-receptor-1-antibody-GTX22350-IHC-2_18121411_528.jpg
VEGF-receptor-1-antibody-GTX22350-IHC-p-1_18121411_416.jpg

Cat No. GTX22350

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P, IHC-Fr, IHC
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

IHC: This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.

Calculated MW

151 kDa. ( Note )

Positive Control

Angiosarcoma

Specificity/Sensitivity

This antibody reacts with a 180 kD protein, known as Flt-1/VEGFR 1 (Vascular Endothelial Growth Factor Receptor 1). The sequence that this antibody recognises is not present in soluble VEGF Receptor 1.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Synthetic peptide: C-AELERKIACCSPPPDYN, corresponding to amino acids 1312-1328 of Human VEGF Receptor 1.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Fms Related Tyrosine Kinase 1,Flt,Flt-1,Vegfr-1,Vegfr1,Flt1

Cellular Localization

Type I membrane protein (Flt1) and soluble (SFlt1).

Background

VEGFR 1 is a cell membrane receptor kinase. It has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.

Database

Research Area

DATA IMAGES
VEGF-receptor-1-antibody-GTX22350-IHC-1_18121411_530.jpg

GTX22350 IHC Image


VEGF-receptor-1-antibody-GTX22350-IHC-2_18121411_528.jpg

GTX22350 IHC Image


VEGF-receptor-1-antibody-GTX22350-IHC-p-1_18121411_416.jpg

GTX22350 IHC Image

Detection of VEGF Receptor 1 by IHC in Human Angiosarcoma