Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100 - 1:2000 |
1:500 |
1:250 - 1:500 |
Not tested in other applications.
Calculated MW
Product Note
This antibody targets VEGFR-1 but has significant cross-reactivity with the VEGFR-2 protein.
Form
Liquid
Buffer
Tris-Glycine, 150mM NaCl
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Mouse
Immunogen
A synthetic peptide made to an internal region of the mouse VEGF Receptor 1 protein (between residues 800-900) [UniProt# P35969]. There is 87% identity between the immunogen used for this production and the VEGF Receptor 2 protein.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
FMS-like tyrosine kinase 1 , AI323757 , Flt-1 , VEGFR-1 , VEGFR1 , sFlt1
Cellular Localization
Cell membrane; Single-pass type I membrane protein,Endosome
Background
Receptor for VEGF and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
Database
Research Area