GeneTex
United States (US)

VEGF Receptor 1 (phospho Tyr1213) antibody

Anti-VEGF Receptor 1 (phospho Tyr1213) antibody used in Western Blot (WB). GTX32184

Cat No. GTX32184

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

151 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of VEGF Receptor 1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Fms Related Tyrosine Kinase 1,Flt,Flt-1,Vegfr-1,Vegfr1,Flt1

Cellular Localization

Cell membrane,Cytoplasm,Endosome,Secreted

Background

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]

Database

Research Area

DATA IMAGES
Anti-VEGF Receptor 1 (phospho Tyr1213) antibody used in Western Blot (WB). GTX32184

GTX32184 WB Image

WB analysis of A10 (A), MDA-MB-231 (B) whole cell lysates using GTX32184 VEGF Receptor 1 (phospho Tyr1213) antibody.

REFERENCE