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VEGF Receptor 2 antibody

Anti-VEGF Receptor 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX80591
Anti-VEGF Receptor 2 antibody used in Western Blot (WB). GTX80591

Cat. No. GTX80591

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
400 μl ($399)
See all VEGF Receptor 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

152 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This VGFR2 antibody is generated from rabbits immunized with a His fusion protein from human VGFR2.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

kinase insert domain receptor , CD309 , FLK1 , VEGFR , VEGFR2

Cellular Localization

Cell junction,Endoplasmic reticulum,Cytoplasm,Nucleus,Cytoplasmic vesicle

Background

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Database

Research Area

DATA IMAGES

Anti-VEGF Receptor 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX80591

GTX80591 IHC-P Image

IHC-P analysis of human breast carcinoma using GTX80591 VEGF Receptor 2 antibody.

Anti-VEGF Receptor 2 antibody used in Western Blot (WB). GTX80591

GTX80591 WB Image

WB analysis of mouse cerebellum tissue lysate (35ug/lane) using GTX80591 VEGF Receptor 2 antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399