APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:100-1:200 |
| 1:50-1:100 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide sequence around phosphorylation site of tyrosine 1175 (K-D-Y(p)-I-V) derived from human VEGF Receptor 2.
Purification
Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
kinase insert domain receptor , CD309 , FLK1 , VEGFR , VEGFR2
Cellular Localization
Cell junction,Endoplasmic reticulum,Cytoplasm,Nucleus,Cytoplasmic vesicle
Background
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
Database
Research Area
DATA IMAGES
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GTX50151 IHC-P Image
IHC-P analysis of human breast carcinoma tissue using GTX50151 VEGF Receptor 2 (phospho Tyr1175) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide
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GTX50151 ICC/IF Image
ICC/IF analysis of methanol-fixed MCF cells using GTX50151 VEGF Receptor 2 (phospho Tyr1175) antibody.
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REFERENCE
There are currently no references for VEGF Receptor 2 (phospho Tyr1175) antibody (GTX50151). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for VEGF Receptor 2 (phospho Tyr1175) antibody (GTX50151). Be the first to share your experience with this product.
