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VMAT2 antibody, C-term

Anti-VMAT2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89638
Anti-VMAT2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89638
Anti-VMAT2 antibody, C-term used in Western Blot (WB). GTX89638

Cat. No. GTX89638

Reference 2

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all VMAT2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-3μg/ml
IHC-P 5μg/ml
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89638-PEP).

Predict Reactivity

Mouse, Rat, Bovine, Dog, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-SYPIGEDEESESD, from the C Terminus of the protein sequence according to NP_003045.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

RRID

AB_10725607

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 18 member A2 , PKDYS2 , SVAT , SVMT , VAT2 , VMAT2

Background

This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments. [provided by RefSeq, Jun 2018]

Database

Research Area

DATA IMAGES

Anti-VMAT2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89638

GTX89638 IHC-P Image

IHC-P analysis of human pancreas using GTX89638 VMAT2 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5μg/ml

Anti-VMAT2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89638

GTX89638 IHC-P Image

IHC-P analysis of human adrenal gland using GTX89638 VMAT2 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 2.5μg/ml

Anti-VMAT2 antibody, C-term used in Western Blot (WB). GTX89638

GTX89638 WB Image

WB analysis of human placenta (A) and human adrenal gland (B) lysate using GTX89638 VMAT2 antibody, C-term.
Dilution : 1μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

Application Reference

Nuber S et al. NPJ Parkinsons Dis 2024; 10 (1) : 47 Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes.
Rajsombath MM et al. J Neurosci 2019; (Epub) Female sex and brain-selective estrogen benefit 帢-synuclein tetramerization and the PD-like motor syndrome in 3K transgenic mice.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399