VR1/ TRPV1 antibody

Cat. No. GTX04108

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, FACS
Reactivity	Human, Rat
Package	100 μg ($429)

See all VR1/ TRPV1 products

Datasheet

View product citations for antibody GTX04108 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	0.25-0.5μg/mL
ICC/IF	5μg/mL
FACS	1-3μg/10⁶ cells

Not tested in other applications.

Calculated MW

95 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4

Preservative

No preservatives

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

E.coli-derived human TRPV1 recombinant protein (Position: E107-A800).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transient receptor potential cation channel subfamily V member 1 , VR1

Cellular Localization

Cell membrane

Background

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Gene ID: 7442 TRPV1
UniProt: Q8NER1 TRPV1

Research Area

DATA IMAGES

GTX04108 ICC/IF Image

ICC/IF analysis of T-47D cells using GTX04108 VR1/ TRPV1 antibody. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins.
Green : Primary antibody
Blue : DAPI
Dilution : 5 μg/mL

GTX04108 FACS Image

FACS analysis of U87 cells using GTX04108 VR1/ TRPV1 antibody.
Blue : Primary antibody
Green : Isotype control
Red : Unlabelled sample
Dilution : 1 μg/1x106 cells

GTX04108 WB Image

WB analysis of various sample lysates using GTX04108 VR1/ TRPV1 antibody.
Loading : 30 μg
Dilution : 0.5 μg/mL

REFERENCE

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REVIEW

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Package

List Price ($)

100 μg

$ 429

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