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VR1/ TRPV1 antibody

Anti-VR1/ TRPV1 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54762
Anti-VR1/ TRPV1 antibody used in Western Blot (WB). GTX54762
Anti-VR1/ TRPV1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54762
Anti-VR1/ TRPV1 antibody used in Western Blot (WB). GTX54762

Cat. No. GTX54762

Reference 4

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr, FACS

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all VR1/ TRPV1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
Not tested in other applications.

Calculated MW

95 kDa. ( Note )

Predict Reactivity

Guinea pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Peptide (C)EDAEVFKDSMVPGEK, corresponding to amino acid residues 824-838 (Intracellular, C-terminus) of rat TRPV1 (Accession  : O35433).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887883

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transient receptor potential cation channel, subfamily V, member 1 , TRPV1_SON , VR.5'sv , Vr1 , Vr1l1

Cellular Localization

Cell membrane

Background

ion channel that demonstrates heat-evoked membrane currents [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-VR1/ TRPV1 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54762

GTX54762 IHC-Fr Image

IHC-Fr analysis of rat DRG tissue using GTX54762 VR1/ TRPV1 antibody.
Panel A : TRPV1 (red) in DRG neurons.
Panel B : Staining with mouse anti-Parvalbumin (green) in the same DRG section.
Panel C : Merge of TRPV1 and Parvalbumin demonstrates colocalization (arrows).

Anti-VR1/ TRPV1 antibody used in Western Blot (WB). GTX54762

GTX54762 WB Image

WB analysis of TRPV1 transfected HEK-293 cell lysate using GTX54762 VR1/ TRPV1 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

Anti-VR1/ TRPV1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54762

GTX54762 ICC/IF Image

ICC/IF analysis of PFA-fixed rat DRG primary culture cells using GTX54762 VR1/ TRPV1 antibody.
Panel A : Primary antibody
Panel B : DNA dye Hoechst 33342
Panel C : Merged images of panels A and B
Dilution : 1:200

Anti-VR1/ TRPV1 antibody used in Western Blot (WB). GTX54762

GTX54762 WB Image

WB analysis of rat DRG lysate using GTX54762 VR1/ TRPV1 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

REFERENCE

Application Reference

AR Liu et al. J Headache Pain 2023; The potent analgesia of intrathecal 2R, 6R-HNK via TRPA1 inhibition in LF-PENS-induced chronic primary pain model
Application : WB, IHC-Fr
Peng JW et al. Mol Pain 2022; 18 : 1.74E+16 LncRNA MEG3-TRPV1 signaling regulates chronic inflammatory pain in rats.
Application : WB
Reactivity : Rat
Qian K et al. Dis Markers 2022; 2022 : 3100943 Transient Receptor Potential Vanilloid-1 (TRPV1) Alleviates Hepatic Fibrosis via TGF-β Signaling.
Application : IHC-P
Reactivity : Human
Ting-Yi Liu et al. bioRxiv 2019; (Epub) It takes two vanilloid ligand bindings per channel to transduce painful capsaicin stimuli.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639