GeneTex
United States (US)

VWF antibody (FITC)

Cat No. GTX28822

Host Sheep
Clonality Polyclonal
Isotype IgG
Application ICC/IF, IHC-Fr, FACS, IHC
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
IHC-Fr 1:50-1:100
FACS Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

309 kDa. ( Note )

Specificity/Sensitivity

The unconjugated immunoglobulin gives no arcs when tested by IEP against human serum. Identity has beenconfirmed by double diffusion (Ouchterlony) against human VWF and an anti-human VWF of knownspecificity.
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.2

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. Protect from light.

Antigen Species

Human

Immunogen

Human von Willebrand Factor Antigen (VWF): Prepared from citrated human plasma. > 95% pure (SDS-

Purification

IgG fraction

Conjugation

Fluorescein isothiocyanate (FITC)

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

F8VWF Antibody , VWD Antibody

Cellular Localization

Secreted. Located in storage granules.

Background

The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE
Package List Price ($)
$ 429