GeneTex

  • Country / Location Selection

United States (US)

VWF antibody [MSVA-521R] HistoMAX™

Recombinant antibody HistoMAX
Anti-VWF antibody [MSVA-521R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04412
Anti-VWF antibody [MSVA-521R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04412
Anti-VWF antibody [MSVA-521R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04412

Cat. No. GTX04412

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 MSVA-521R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($629),
100 μl ($299)
See all VWF products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-1:100

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
Not tested in other applications.

Calculated MW

309 kDa. ( Note )

Positive Control

Colon: A moderate to strong endothelial vWF immunostaining should be seen in a fraction of blood vessels.

Negative Control

Colon: vWF immunostaining should be completely absent in epithelial and muscular cells.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human vWF protein (aa1815-1939)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

von Willebrand factor , F8VWF , VWD

Cellular Localization

Secreted , Secreted, extracellular space, extracellular matrix

Background

This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]

Database

Research Area

DATA IMAGES

Anti-VWF antibody [MSVA-521R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04412

GTX04412 IHC-P Image

IHC-P analysis of human duodenum Brunner's gland tissue using GTX04412 VWF antibody [MSVA-521R] HistoMAX™.
In the Brunner gland endothelial VWF immunostaining is strongest in venules.

Anti-VWF antibody [MSVA-521R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04412

GTX04412 IHC-P Image

IHC-P analysis of human ovarian high-grade serous carcinoma (HGSC) tissue using GTX04412 VWF antibody [MSVA-521R] HistoMAX™.
Serous high grade carcinoma showing distinct endothelial VWF staining in a subset of intratumoral vessels.

Anti-VWF antibody [MSVA-521R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04412

GTX04412 IHC-P Image

IHC-P analysis of human skeletal muscle tissue using GTX04412 VWF antibody [MSVA-521R] HistoMAX™.
In skeletal muscle endothelial VWF immunostaining is strong in postcapillary venules and somewhat weaker in capillaries.

REFERENCE

There are currently no references for VWF antibody [MSVA-521R] HistoMAX™ (GTX04412). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for VWF antibody [MSVA-521R] HistoMAX™ (GTX04412). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 629
$ 299