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VWF antibody [VW92-3]

Cat. No. GTX48264

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 VW92-3

Isotype

 IgG2a

Application

 WB, IHC-P, IHC-Fr, ELISA

Reactivity

 Human
Package
200 μg ($489)
See all vWF products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 5-10 μg/ml
IHC-P 5-10μg/ml
IHC-Fr 5-10μg/ml
ELISA 1-10μg/ml

Note :

WB
Useful under non-reducing.
Not tested in other applications.

Calculated MW

309 kDa. ( Note )

Product Note

This antibody specifically recognizes human von Willebrand Factor V8 Protease Fragment III (N-terminal trypsin and plasmin sensitive region). This antibody does not react with bovine vWF.

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human plasma von Willebrand Factor.

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

F8VWF , VWD , VWF , von Willebrand factor , von Willebrand Factor

Cellular Localization

Secreted,Extracellular space,Extracellular matrix

Background

This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 489