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United States (US)

VWF antibody

Cat. No. GTX74137

Reference 4

Host

 Sheep

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-Fr, FACS, ELISA, Immunodiffusion

Reactivity

 Human, Rat
Package
50 μl ($169)
See all VWF products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
ELISA Assay dependent
Immunodiffusion Neat
Not tested in other applications.

Calculated MW

309 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Glycine buffered saline, 0.01% Benzamidine, 0.1%EACA, 1mM EDTA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human von Willebrand factor prepared from citrated human plasma

Purification

Purified by ion exchange chromatography

Conjugation

Unconjugated

RRID

AB_377840

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

von Willebrand factor , F8VWF , VWD

Cellular Localization

Secreted

Background

This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]

Database

Research Area

REFERENCE

Application Reference

Portillo JC et al. Cells 2024; 13 (5) Advanced Glycation End Products Upregulate CD40 in Human Retinal Endothelial and M?ller Cells: Relevance to Diabetic Retinopathy.
Vos S et al. Invest Ophthalmol Vis Sci 2023; 64 (7) : 17 CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression.
Yin T et al. Bioact Mater 2022; 10 : 378-396 Two-stage degradation and novel functional endothelium characteristics of a 3-D printed bioresorbable scaffold.
Application : ICC/IF
Perriard G et al. J Neuroinflammation 2015; 12 : 119 Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
Application : ICC/IF
Reactivity : Human
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SDS
Sodium Azide.pdf
Package List Price ($)
$ 169