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Villin antibody [rVIL1/1325]

Anti-Villin antibody [rVIL1/1325] used in IHC (Paraffin sections) (IHC-P). GTX02738
Anti-Villin antibody [rVIL1/1325] used in Protein Array (Protein Array). GTX02738
Anti-Villin antibody [rVIL1/1325] used in IHC (Paraffin sections) (IHC-P). GTX02738

Cat. No. GTX02738

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 rVIL1/1325

Isotype

 IgG1

Application

 IHC-P, Protein Array

Reactivity

 Human
Package
100 μg ($529)
See all Villin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2 μg/ml
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Product Note

This antibody could recongnize Merkel cells of the skin.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A recombinant fragment (around aa179-311) of human Villin protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

villin 1 , D2S1471 , VIL

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Villin antibody [rVIL1/1325] used in IHC (Paraffin sections) (IHC-P). GTX02738

GTX02738 IHC-P Image

IHC-P analysis of human small intestinal carcinoma section using GTX02738 Villin antibody [rVIL1/1325].

Anti-Villin antibody [rVIL1/1325] used in Protein Array (Protein Array). GTX02738

GTX02738 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using Villin-Monospecific Recombinant Mouse Monoclonal Antibody (rVIL1/1325) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Anti-Villin antibody [rVIL1/1325] used in IHC (Paraffin sections) (IHC-P). GTX02738

GTX02738 IHC-P Image

IHC-P analysis of human small intestinal carcinoma section using GTX02738 Villin antibody [rVIL1/1325].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529