APPLICATION
Application Note
Immunohistochemistry (IHC) 1:50-1:100 using polymer system or streptavidin-biotin system. Formalin-fixed paraffin-embedded (FFPE) tissue sections and cell smears do not require antigen retrieval.
Calculated MW
Positive Control
Sarcomas, melanomas, Hela cells
PROPERTIES
Form
Liquid
Buffer
10mM PO₄, 200mM NaCl 1% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
3 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Purified human Vimentin
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
vimentin
Cellular Localization
Cytoplasm , Cytoplasm, cytoskeleton
Background
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
Database
Research Area
REFERENCE
There are currently no references for Vimentin antibody (GTX82958). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Vimentin antibody (GTX82958). Be the first to share your experience with this product.