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Vitamin D Receptor (phospho Ser51) antibody

Anti-Vitamin D Receptor (phospho Ser51) antibody used in Western Blot (WB). GTX86040
Anti-Vitamin D Receptor (phospho Ser51) antibody used in Western Blot (WB). GTX86040

Cat. No. GTX86040

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all Vitamin D Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Vitamin D Receptor (16-65).

Purification

Purified by antigen-affinity chromatography. Non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

NR1I1 , PPP1R163 , VDR , vitamin D (1,25 dihydroxyvitamin D3) receptor , Vitamin D Receptor , vitamin D (1,25- dihydroxyvitamin D3) receptor

Cellular Localization

Nucleus,Cytoplasm

Background

This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-Vitamin D Receptor (phospho Ser51) antibody used in Western Blot (WB). GTX86040

GTX86040 WB Image

WB analysis of COLO205 cells treated with Insulin 0.01U/ml (15mins) lysate using GTX86040 Vitamin D Receptor (phospho Ser51) antibody. The lane on the right is blocked with the synthesized peptide.

Anti-Vitamin D Receptor (phospho Ser51) antibody used in Western Blot (WB). GTX86040

GTX86040 WB Image

WB analysis of COLO cell lysate using GTX86040 Vitamin D Receptor (phospho Ser51) antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399