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WBP2 antibody, C-term

KO/KD Overexpression
Anti-WBP2 antibody, C-term used in Flow cytometry (FACS). GTX81293
Anti-WBP2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX81293
Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293
Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293
Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293
Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293
Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293
Anti-WBP2 antibody, C-term used in Immunoprecipitation (IP). GTX81293
Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293

Cat. No. GTX81293

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS, IP

Reactivity

 Human
Package
400 μl ($399)
See all WBP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:10-1:50
FACS 1:10-1:50
IP Assay dependent
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 186-212 amino acids from the C-terminal region of human WBP2.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

RRID

AB_11165121

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

WW domain binding protein 2 , DFNB107 , GRAMD6 , WBP-2

Cellular Localization

Cytoplasm,Nucleus

Background

The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein that is a transcriptional coactivator of estrogen receptor alpha and progesterone receptor. Defects in this gene have been associated with hearing impairment. [provided by RefSeq, Jan 2017]

Database

Research Area

DATA IMAGES

Anti-WBP2 antibody, C-term used in Flow cytometry (FACS). GTX81293

GTX81293 FACS Image

FACS analysis of HepG2 cells using GTX81293 WBP2 antibody, C-term.
Top histogram : negative control
Bottom histogram : HepG2 cells

Anti-WBP2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX81293

GTX81293 IHC-P Image

IHC-P analysis of human brain tissue using GTX81293 WBP2 antibody, C-term.

Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293

GTX81293 WB Image

WB analysis of A2058 cell lysate (35ug/lane) using GTX81293 WBP2 antibody, C-term.

Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293

GTX81293 WB Image

KO/KD Overexpression

The data was published in the journal Cell Death Dis in 2018. PMID: 29497031

Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293

GTX81293 WB Image

KO/KD

The data was published in the 2018 in Br J Cancer. PMID: 29937544

Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293

GTX81293 WB Image

KO/KD

The data was published in the 2018 in Br J Cancer. PMID: 29937544

Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293

GTX81293 WB Image

The data was published in the 2018 in Br J Cancer. PMID: 29937544

Anti-WBP2 antibody, C-term used in Immunoprecipitation (IP). GTX81293

GTX81293 IP Image

The data was published in the 2018 in Br J Cancer. PMID: 29937544

Anti-WBP2 antibody, C-term used in Western Blot (WB). GTX81293

GTX81293 WB Image

The data was published in the journal Cell Death Dis in 2018. PMID: 29497031

REFERENCE

Application Reference

Chen S et al. Br J Cancer 2018; (Epub) interaction of wbp2 with erα increases * resistance of breast cancer cells by modulating mdr1 transcription.
Application : WB, IHC-P
Reactivity : Human
Chen S et al. Cell Death Dis 2018; 9 (3) : 347 WW domain-binding protein 2 acts as an oncogene by modulating the activity of the glycolytic enzyme ENO1 in glioma.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399