APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:3000 |
Not tested in other applications.
Calculated MW
Positive Control
HepG2
Predict Reactivity
Mouse, Rat, Bovine(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.38 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human WWOX. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_1241457
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
WW domain containing oxidoreductase , D16S432E , EIEE28 , FOR , FRA16D , HHCMA56 , PRO0128 , SCAR12 , SDR41C1 , WOX1
Cellular Localization
Cytoplasm , Nucleus , Mitochondrion , Golgi apparatus
Background
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. [provided by RefSeq]
Database
Research Area
DATA IMAGES
![Anti-WWOX antibody [N1N2], N-term used in Western Blot (WB). GTX108011](/templates/default/js/lightbox/images/loading.gif "Anti-WWOX antibody [N1N2], N-term used in Western Blot (WB). GTX108011")
|
GTX108011 WB Image
Sample (30 ug of whole cell lysate)
A: Hep G2 (GTX27900)
10% SDS PAGE
GTX108011 diluted at 1:1000
|
REFERENCE
There are currently no references for WWOX antibody [N1N2], N-term (GTX108011). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for WWOX antibody [N1N2], N-term (GTX108011). Be the first to share your experience with this product.
![Anti-WWOX antibody [N1N2], N-term used in Western Blot (WB). GTX108011](/upload/website/prouct_img/small/GTX108011/GTX108011_WB_w_23060120_684.webp "Anti-WWOX antibody [N1N2], N-term used in Western Blot (WB). GTX108011")
![Anti-WWOX antibody [N1N2], N-term used in Western Blot (WB). GTX108011](/upload/website/prouct_img/normal/GTX108011/GTX108011_WB_w_23060120_684.webp "Anti-WWOX antibody [N1N2], N-term used in Western Blot (WB). GTX108011")