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WWOX (phospho Tyr33) antibody

Orthogonal
Anti-WWOX (phospho Tyr33) antibody used in IHC (Paraffin sections) (IHC-P). GTX55345
Anti-WWOX (phospho Tyr33) antibody used in Western Blot (WB). GTX55345

Cat. No. GTX55345

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all WWOX products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of tyrosine 33 (W-V-Y(p)-Y-A) derived from human WWOX.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

WW domain containing oxidoreductase , D16S432E , EIEE28 , FOR , FRA16D , HHCMA56 , PRO0128 , SCAR12 , SDR41C1 , WOX1

Cellular Localization

Cytoplasm,Nucleus,Mitochondrion,Golgi apparatus

Background

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Database

Research Area

DATA IMAGES

Anti-WWOX (phospho Tyr33) antibody used in IHC (Paraffin sections) (IHC-P). GTX55345

GTX55345 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX55345 WWOX (phospho Tyr33) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

Anti-WWOX (phospho Tyr33) antibody used in Western Blot (WB). GTX55345

GTX55345 WB Image

Orthogonal

WB analysis of extracts from HepG2 cells treated with PMA using GTX55345 WWOX (phospho Tyr33) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399