APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
10 μg/ml |
Note :
IHC-P
Heat induced antigen retrieval in pH 6.0 citrate buffer
|
Not tested in other applications.
Calculated MW
Predict Reactivity
Elephant, Gibbon, Gorilla, Marmoset, Opossum, Panda, Platypus(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from internal region of human WNT8B.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
Wnt family member 8B , WNT8B
Cellular Localization
Secreted,Extracellular space,Extracellular matrix
Background
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX85814 IHC-P Image
IHC-P analysis of human brain, basal nucleus of meynert tissue using GTX85814 Wnt8b antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX85814 IHC-P Image
IHC-P analysis of human brain, cortex tissue using GTX85814 Wnt8b antibody. Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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