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United States (US)

XPA antibody

Cat No. GTX10905

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
50 μl ($299)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1/5,000
IHC-P 1/50

Note :

IHC-P
This product requires heat mediated treatment of paraffin sections.

Not tested in other applications.

Calculated MW

31 kDa. ( Note )

Product Note

This antibody recognizes both normal and recombinant XPA, and shows no cross reactivity with other XP proteins.

PROPERTIES

Form

Liquid

Buffer

Serum

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant human XPA

Purification

Serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

XPA, DNA damage recognition and repair factor , XP1 , XPAC

Cellular Localization

Nucleus

Background

This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]

Database

Research Area

REFERENCE

There are currently no references for XPA antibody (GTX10905). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for XPA antibody (GTX10905). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 299