*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
NT2D1 , IMR32 , U87-MG , MCF-7
Mouse, Rat, Bovine(>80% identity)
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.67 mg/ml (Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the C-terminus region of human XPC. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
XPC complex subunit, DNA damage recognition and repair factor , RAD4 , XP3 , XPCC , p125
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
GTX102840 WB Image
Whole cell extract (30 µg) was separated by 5% SDS-PAGE, and the membrane was blotted with XPC antibody [C2C3], C-term (GTX102840) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
GTX102840 IHC-P Image
Immunohistochemical analysis of paraffin-embedded human breast cancer, using XPC(GTX102840) antibody at 1:250 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
GTX102840 ICC/IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using XPC(GTX102840) antibody at 1:500 dilution.