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XPC antibody [C2C3], C-term

Anti-XPC antibody [C2C3], C-term used in Western Blot (WB). GTX102840
Anti-XPC antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX102840
Anti-XPC antibody [C2C3], C-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX102840

Cat No. GTX102840

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human
Package
100 μl ($319),
25 μl ($169)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

106 kDa. ( Note )

Positive Control

NT2D1 , IMR32 , U87-MG , MCF-7

Predict Reactivity

Mouse, Rat, Bovine(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.67 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human XPC. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

XPC complex subunit, DNA damage recognition and repair factor , RAD4 , XP3 , XPCC , p125

Cellular Localization

Nucleus

Background

This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES
Anti-XPC antibody [C2C3], C-term used in Western Blot (WB). GTX102840

GTX102840 WB Image

Whole cell extract (30 µg) was separated by 5% SDS-PAGE, and the membrane was blotted with XPC antibody [C2C3], C-term (GTX102840) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-XPC antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX102840

GTX102840 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human breast cancer, using XPC(GTX102840) antibody at 1:250 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-XPC antibody [C2C3], C-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX102840

GTX102840 ICC/IF Image

Immunofluorescence analysis of paraformaldehyde-fixed A431, using XPC(GTX102840) antibody at 1:500 dilution.

REFERENCE
There are currently no references for XPC antibody [C2C3], C-term (GTX102840). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for XPC antibody [C2C3], C-term (GTX102840). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Thimerosal.pdf