*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
IMR32 , U87-MG
Rat, Bovine, Chimpanzee(>80% identity)
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the center region of human ERCC2. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
COFS2 antibody, EM9 antibody, MGC102762 antibody, MGC126218 antibody, MGC126219 antibody, TTD antibody, XPD antibody, ERCC2 antibody, basic transcription factor 2 80 kDa subunit antibody, TFIIH p80 antibody, TFIIH basal transcription factor complex helicase subunit antibody, xeroderma pigmentosum complementary group D antibody, TFIIH basal transcription factor complex 80 kDa subunit antibody, TFIIH basal transcription factor complex helicase XPD subunit antibody, DNA excision repair protein ERCC-2 antibody, CXPD antibody, xeroderma pigmentosum group D-complementing protein antibody, BTF2 p80 antibody, DNA repair protein complementing XP-D cells antibody, TFIIH 80 kDa subunit antibody, "excision repair cross-complementing rodent repair deficiency, complementation group 2 antibody"
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]