GeneTex
United States (US)

XRCC3 antibody [10F1/6]

Cat No. GTX30140

Host Mouse
Clonality Monoclonal
Clone Name 10F1/6
Isotype IgG1
Application WB, ICC/IF, IHC-P
Reactivity Human, Rat, Sheep, Bovine, Primate
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
ICC/IF 1:10 - 1:500
IHC-P 1:10 - 1:500
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Specificity/Sensitivity

This antibody does not cross-react with Rad51B, Rad51C, Rad51D, Rad51, or XRCC2 in Western analysis.
This product does not react with Mouse.

Predict Reactivity

Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.1% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

His-tagged human XRCC3, over-expressed in E. coli [UniProt# O43542]

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

X-Ray Repair Cross Complementing 3,Cmm6,Xrcc3

Cellular Localization

Nucleus

Background

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq]

Database

Research Area

REFERENCE
Package List Price ($)
$ 339