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XRCC3 antibody

Anti-XRCC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX32975
Anti-XRCC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX32975
Anti-XRCC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX32975
Anti-XRCC3 antibody used in Western Blot (WB). GTX32975
Anti-XRCC3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32975
Anti-XRCC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX32975

Cat No. GTX32975

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 62-346 of human XRCC3 (NP_001093588.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

X-ray repair cross complementing 3 , CMM6

Cellular Localization

Nucleus,Cytoplasm,Mitochondrion

Background

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-XRCC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX32975

GTX32975 IHC-P Image

IHC-P analysis of rat brain tissue using GTX32975 XRCC3 antibody.
Dilution : 1:100

Anti-XRCC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX32975

GTX32975 IHC-P Image

IHC-P analysis of human colon tissue using GTX32975 XRCC3 antibody.
Dilution : 1:100

Anti-XRCC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX32975

GTX32975 IHC-P Image

IHC-P analysis of human stomach tissue using GTX32975 XRCC3 antibody.
Dilution : 1:200

Anti-XRCC3 antibody used in Western Blot (WB). GTX32975

GTX32975 WB Image

WB analysis of HL-60 cell lysate using GTX32975 XRCC3 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-XRCC3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32975

GTX32975 ICC/IF Image

ICC/IF analysis of U2OS cell using GTX32975 XRCC3 antibody.
Blue : DAPI

Anti-XRCC3 antibody used in IHC (Paraffin sections) (IHC-P). GTX32975

GTX32975 IHC-P Image

IHC-P analysis of rat testis tissue using GTX32975 XRCC3 antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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