GeneTex

  • Country / Location Selection

United States (US)

XRCC4 antibody

Anti-XRCC4 antibody used in IHC (Paraffin sections) (IHC-P). GTX01029
Anti-XRCC4 antibody used in Western Blot (WB). GTX01029

Cat. No. GTX01029

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($429)
See all XRCC4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.5μg/ml
IHC-P 0.5-1μg/ml

Note :

IHC-P
Antigen retreival by heat
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Product Note

Superfamily members of XRCC4 are not reactive to this antibody.

PROPERTIES

Form

Liquid

Buffer

5mg BSA, 0.9mg NaCl, 0.2mg Na₂HPO₄

Preservative

0.05mg Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human XRCC4 (49-75aa ESEISQEADDMAMEKGKYVGELRKALL).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

X-ray repair cross complementing 4 , SSMED , XRCC4 , Xray repair cross complementing 4

Cellular Localization

Nucleus

Background

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site. [provided by RefSeq, Oct 2019]

Database

Research Area

DATA IMAGES

Anti-XRCC4 antibody used in IHC (Paraffin sections) (IHC-P). GTX01029

GTX01029 IHC-P Image

IHC-P analysis of human intestinal cancer tissue using GTX01029 XRCC4 antibody.
Dilution : 1μg/ml

Anti-XRCC4 antibody used in Western Blot (WB). GTX01029

GTX01029 WB Image

WB analysis of various sample lysates using GTX01029 XRCC4 antibody.
Lane 1 : SW620 cell lysate
Lane 2 : A431 cell lysate
Dilution : 0.5μg/ml

REFERENCE

There are currently no references for XRCC4 antibody (GTX01029). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for XRCC4 antibody (GTX01029). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 429