GeneTex

  • Country / Location Selection

United States (US)

YB1 antibody [rYBX1/2430]

Anti-YB1 antibody [rYBX1/2430] used in IHC (Paraffin sections) (IHC-P). GTX02744

Cat. No. GTX02744

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 rYBX1/2430

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all YB1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

36 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human full-length YBX1 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Y-box binding protein 1 , BP-8 , CBF-A , CSDA2 , CSDB , DBPB , EFI-A , MDR-NF1 , NSEP-1 , NSEP1 , YB-1 , YB1

Cellular Localization

Cytoplasm , Nucleus , Secreted

Background

This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-YB1 antibody [rYBX1/2430] used in IHC (Paraffin sections) (IHC-P). GTX02744

GTX02744 IHC-P Image

IHC-P analysis of human prostate carcinoma section using GTX02744 YB1 antibody [rYBX1/2430].

REFERENCE

There are currently no references for YB1 antibody [rYBX1/2430] (GTX02744). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for YB1 antibody [rYBX1/2430] (GTX02744). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 529