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ZAP70 antibody [ZAP-03]

Anti-ZAP70 antibody [ZAP-03] used in Western Blot (WB). GTX00530
Anti-ZAP70 antibody [ZAP-03] used in Western Blot (WB). GTX00530

Cat No. GTX00530

Host

Mouse

Clonality

Monoclonal

Clone Name

ZAP-03

Isotype

IgG1

Application

WB, ICC/IF, FACS

Reactivity

Human
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
FACS Assay dependent
Not tested in other applications.

Calculated MW

70 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Bacterially expressed fusion protein representing C-terminal part (160 amino acids) of human ZAP70 with histidine tag

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ADMIO2 , IMD48 , SRK , STCD , STD , TZK , ZAP70 , zeta chain of T cell receptor associated protein kinase 70

Cellular Localization

Cytoplasm,Cell membrane

Background

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-ZAP70 antibody [ZAP-03] used in Western Blot (WB). GTX00530

GTX00530 WB Image

WB analysis of HPB-ALL (Lane 1, 3) and Ramos cell (Lane 2, 4) lysates using GTX00530 ZAP70 antibody [ZAP-03].
Lane 1, 2 : GTX00530
Lane 3, 4 : mouse IgG1 isotype control
Diultion : 0.5μg/ml

Anti-ZAP70 antibody [ZAP-03] used in Western Blot (WB). GTX00530

GTX00530 WB Image

WB analysis of HPB-ALL cell lysate using GTX00530 ZAP70 antibody [ZAP-03].
Lane 1, 2, 3, 4 : GTX00530 (Dilution : 4, 2, 1, 0.5 μg/ml)
Lane 5 : anti-ZAP-70 comparative antibody
Lane 6 : mouse IgG1 isotype control

REFERENCE

There are currently no references for ZAP70 antibody [ZAP-03] (GTX00530). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for ZAP70 antibody [ZAP-03] (GTX00530). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319