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ZC3H12B antibody

Anti-ZC3H12B antibody used in Western Blot (WB). GTX85196
Anti-ZC3H12B antibody used in IHC (Paraffin sections) (IHC-P). GTX85196

Cat. No. GTX85196

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all ZC3H12B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Mouse Brain Tissue Lysate(GTX27934)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

ZC3H12B antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZC3H12B.The immunogen is located within the first 50 amino acids of ZC3H12B.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

zinc finger CCCH-type containing 12B , CXorf32 , MCPIP2

Background

ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).

Database

DATA IMAGES

Anti-ZC3H12B antibody used in Western Blot (WB). GTX85196

GTX85196 WB Image

WB analysis of mouse brain tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX85196 ZC3H12B antibody.
Working concentration : 1 μg/ml

Anti-ZC3H12B antibody used in IHC (Paraffin sections) (IHC-P). GTX85196

GTX85196 IHC-P Image

IHC-P analysis of human brain tissue using GTX85196 ZC3H12B antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399