0.01M PBS, 1% BSA
15mM Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Batch dependent (Please refer to the vial label for the specific concentration.)
synthetic peptide corresponding to amino acids 138-154 of human α1,2-mannosidase IA with N-terminal added cysteine, conjugated to KLH. The corresponding sequence is identical in mouse.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
mannosidase alpha class 1A member 1 , HUMM3 , HUMM9 , MAN9
Alpha 1,2-Mannosidase IA is a Type II transmembrane Golgi-resident enzyme that belongs to class I alpha 1,2- Mannosidases (glycosylhydrolase family 47). Alpha 1,2-Mannosidases play an essential role in the maturation of N-glycans to hybrid and complex oligosaccharides in mammalian cells. They can be classified into three subgroups according to their enzymatic activities. The second subgroup includes mammalian Golgi alpha 1,2-Mannosidases IA, IB, and IC. It has been suggested that Golgi mannosidases from this subgroup may play a role in the ERAD (endoplasmic reticulum-associated degradation) of defective glycoproteins.