GeneTex
United States (US)

alpha 1 Antichymotrypsin antibody

Cat No. GTX29374

Host Rabbit
Clonality Polyclonal
Application IHC-P, IHC-Fr
Reactivity Human
APPLICATION

Application Note

IHC: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. Staining Protocol: We suggest an incubation period of 30-60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user.

Calculated MW

48 kDa. ( Note )

Specificity/Sensitivity

The antibody is specific against human alpha-1-antichymotrypsin. This antibody stains monocytes and macrophages in human tissues and does not stain any other cell type.
PROPERTIES

Form

Liquid

Buffer

Liquid antiserum

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Alpha-1-antichymotrypsin isolated from human serum

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Serpin Family A Member 3,Aact,Act,Gig24,Gig25,Serpina3

Cellular Localization

Extracellular

Background

The protein is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variation in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Database

Research Area

Package List Price ($)
$ 289