GeneTex
United States (US)

alpha 1 Antitrypsin antibody

GTX29373_IHC-P_18121410_281.jpg

Cat No. GTX29373

Host Rabbit
Clonality Polyclonal
Application IHC-P
Reactivity Human
APPLICATION

Application Note

For IHC-P: Use at a dilution of 1:25-1:50 in an ABC method. An incubation of 30 minutes at RT is recommended. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

47 kDa. ( Note )

Positive Control

Tonsil

Specificity/Sensitivity

The antibody is specific against human alpha-1-antitrypsin. This antibody stains macrophages in human tissues and does not stain any other cell type.
PROPERTIES

Form

Liquid

Buffer

PBS, ph7.2 containing 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Alpha-1-antitrypsin isolated from human serum.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Serpin Family A Member 1,A1A,A1At,Aat,Pi,Pi1,Pro2275,Alpha1At,Nnif,Serpina1

Cellular Localization

Cytoplasmic

Background

alpha 1 Antitrypsin is a plasma protein synthesised in the liver. It consists of a single polypeptide chain and has a molecular weight of 52 kDa. A serine protease inhibitor, its primary function is the protection of lung tissue from the action of neutrophil elastase. The average level of alpha 1 Antitrypsin in plasma is 1.3 g/l.

Database

Research Area

DATA IMAGES
GTX29373_IHC-P_18121410_281.jpg

GTX29373 IHC-P Image

IHC-P analysis of human tonsil using alpha 1 Antitrypsin antibody.