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alpha 1 Catenin (phospho Ser641) antibody

Orthogonal
Anti-alpha 1 Catenin (phospho Ser641) antibody used in Western Blot (WB). GTX50338
Anti-alpha 1 Catenin (phospho Ser641) antibody used in Western Blot (WB). GTX50338

Cat. No. GTX50338

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($399)
See all alpha 1 Catenin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
Not tested in other applications.

Calculated MW

100 kDa. ( Note )

Predict Reactivity

Mouse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of serine 641 (D-D-S(p)-D-F) derived from human alpha 1 Catenin.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

catenin alpha 1 , CAP102 , MDPT2

Cellular Localization

Cell junction

Background

This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016]

Database

Research Area

DATA IMAGES

Anti-alpha 1 Catenin (phospho Ser641) antibody used in Western Blot (WB). GTX50338

GTX50338 WB Image

Orthogonal

WB analysis of extracts from HeLa cells untreated or treated with starvation using GTX50338 alpha 1 Catenin (phospho Ser641) antibody.

Anti-alpha 1 Catenin (phospho Ser641) antibody used in Western Blot (WB). GTX50338

GTX50338 WB Image

Orthogonal

WB analysis of extracts from HT-29 cells treated with serum or calf intestinal phosphatase (CIP) using GTX50338 alpha 1 Catenin (phospho Ser641) antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399