APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
6 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Bovine, Dog, Hamster, Elephant, Gorilla, Marmoset(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human ADRA1B.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375254
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
adrenoceptor alpha 1B , ADRA1 , ADRA1B , ALPHA1BAR , alpha 1b Adrenergic Receptor
Cellular Localization
Nucleus membrane,Cell membrane,Cytoplasm,Membrane,Caveola
Background
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX70699 IHC-P Image
IHC-P analysis of human kidney, collecting duct tissue using GTX70699 alpha 1b Adrenergic Receptor antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX70699 IHC-P Image
IHC-P analysis of human ovary, carcinoma tissue using GTX70699 alpha 1b Adrenergic Receptor antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX70699 IHC-P Image
IHC-P analysis of artery tissue using GTX70699 alpha 1b Adrenergic Receptor antibody.
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GTX70699 IHC-P Image
IHC-P analysis of human breast, carcinoma tissue using GTX70699 alpha 1b Adrenergic Receptor antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX70699 IHC-P Image
IHC-P analysis of brain medulla nerve fibers tissue using GTX70699 alpha 1b Adrenergic Receptor antibody.
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GTX70699 IHC-P Image
IHC-P analysis of uterus, smooth muscle tissue using GTX70699 alpha 1b Adrenergic Receptor antibody.
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REFERENCE
There are currently no references for alpha 1b Adrenergic Receptor antibody (GTX70699). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for alpha 1b Adrenergic Receptor antibody (GTX70699). Be the first to share your experience with this product.