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alpha 2a Adrenergic Receptor antibody

Anti-alpha 2a Adrenergic Receptor antibody used in IHC (Frozen sections) (IHC-Fr). GTX80804

Cat. No. GTX80804

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-Fr

Reactivity

 Human, Mouse, Rat
Package
50 μl ($399)
See all alpha 2a Adrenergic Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr 5-10 μg/mL
Not tested in other applications.

Calculated MW

49 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

(C)KASRWRGRQNREKR

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

adrenoceptor alpha 2A , ADRA2 , ADRA2R , ADRAR , ALPHA2AAR , ZNF32

Cellular Localization

Cell membrane

Background

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-alpha 2a Adrenergic Receptor antibody used in IHC (Frozen sections) (IHC-Fr). GTX80804

GTX80804 IHC-Fr Image

IHC-Fr analysis of rat brain tissue using GTX80804 alpha 2a Adrenergic Receptor antibody. Labeling is confined to synaptic boutons.
Red : Primary antibody
Blue : DAPI

REFERENCE

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REVIEW

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Package List Price ($)
$ 399