GeneTex
United States (US)

alpha 2c Adrenergic Receptor antibody [C2C3], C-term

GTX100334_WB_19011506_921.jpg
GTX100334_39890_IHC_19011506_519.jpg

Cat No. GTX100334

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Positive Control

HeLa , HepG2

Predict Reactivity

Mouse, Rat(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.62mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human alpha 2c Adrenergic Receptor. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ADRA2L2 antibody, ADRA2RL2 antibody, ADRARL2 antibody, ALPHA2CAR antibody, ADRA2C antibody, alpha-2C adrenoceptor antibody, alpha-2C adrenoreceptor antibody, alpha-2C-adrenergic receptor antibody, alpha-2CAR antibody, alpha-2 adrenergic receptor subtype C4 antibody, alpha2-AR-C4 antibody, alpha-2C adrenergic receptor antibody, "adrenergic, alpha-2C-, receptor antibody"

Cellular Localization

Cell membrane

Background

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX100334_WB_19011506_921.jpg

GTX100334 WB Image

Sample (30 ug of whole cell lysate)
A: Hela
10% SDS PAGE
Alpha-2C adrenergic receptor antibody
GTX100334 diluted at 1:1000

GTX100334_39890_IHC_19011506_519.jpg

GTX100334 IHC-P Image

Immunohistochemical analysis of paraffin-embedded ES2 xenograft, using alpha 2c Adrenergic Receptor(GTX100334) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169