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alpha 2c Adrenergic Receptor antibody

Anti-alpha 2c Adrenergic Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX54924
Anti-alpha 2c Adrenergic Receptor antibody used in Western Blot (WB). GTX54924

Cat No. GTX54924

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of alpha 2c Adrenergic Receptor. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

adrenoceptor alpha 2C , ADRA2L2 , ADRA2RL2 , ADRARL2 , ALPHA2CAR

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-alpha 2c Adrenergic Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX54924

GTX54924 IHC-P Image

IHC-P analysis of formalin fixed human breast cancer tissue section using GTX54924 alpha 2c Adrenergic Receptor antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Anti-alpha 2c Adrenergic Receptor antibody used in Western Blot (WB). GTX54924

GTX54924 WB Image

WB analysis of Jurkat (A), mouse liver (B), rat liver (C) whole cell lysates using GTX54924 alpha 2c Adrenergic Receptor antibody.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf