*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Rat, Dog, Guinea pig, Gibbon, Gorilla(>80% identity)
PBS, 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human ADRA2C.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
adrenoceptor alpha 2C , ADRA2C , ADRA2L2 , ADRA2RL2 , ADRARL2 , ALPHA2CAR , alpha 2c Adrenergic Receptor
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
GTX71447 IHC-P Image
IHC-P analysis of human artery, smooth muscle tissue using GTX71447 alpha 2c Adrenergic Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval