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alpha Actinin 1 antibody

Anti-alpha Actinin 1 antibody used in Western Blot (WB). GTX55505
Anti-alpha Actinin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55505
Anti-alpha Actinin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55505
Anti-alpha Actinin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55505

Cat No. GTX55505

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Monkey
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

103 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human ACTN1 (NP_001123477.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

actinin alpha 1 , BDPLT15

Cellular Localization

Cytoplasm, cytoskeleton,Cell membrane,Cell junction

Background

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 87 ACTN1
  • UniProt: P12814 ACTN1

Research Area

DATA IMAGES

Anti-alpha Actinin 1 antibody used in Western Blot (WB). GTX55505

GTX55505 WB Image

WB analysis of various sample lysates using GTX55505 alpha Actinin 1 antibody.
Dilution : 1:500
Loading : 25μg per lane

Anti-alpha Actinin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55505

GTX55505 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX55505 alpha Actinin 1 antibody.
Dilution : 1:100

Anti-alpha Actinin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55505

GTX55505 IHC-P Image

IHC-P analysis of human esophagus tissue using GTX55505 alpha Actinin 1 antibody.
Dilution : 1:100

Anti-alpha Actinin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55505

GTX55505 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX55505 alpha Actinin 1 antibody.
Dilution : 1:100

REFERENCE

There are currently no references for alpha Actinin 1 antibody (GTX55505). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for alpha Actinin 1 antibody (GTX55505). Be the first to share your experience with this product.
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339